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Molecular Dynamics Simulation of Shear- and Stretch-Induced Dissociation of P-Selectin/PSGL-1 Complex

By mediating the tethering and rolling of leukocytes on vascular surfaces, the interactions between P-selectin and the P-selectin glycoprotein ligand 1 (PSGL-1) play crucial roles during inflammation cascade. Tensile stretch produced by rolling leukocytes and shear stress exerted by blood flow const...

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Bibliografski detalji
Glavni autori: Kang, Yingyong, Lü, Shouqin, Ren, Peng, Huo, Bo, Long, Mian
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250688/
https://ncbi.nlm.nih.gov/pubmed/22225804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.11.4002
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