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Low Spring Constant Regulates P-Selectin-PSGL-1 Bond Rupture
Forced dissociation of selectin-ligand bonds is crucial to such biological processes as leukocyte recruitment, thrombosis formation, and tumor metastasis. Although the bond rupture has been well known at high loading rate r(f) (≥10(2) pN/s), defined as the product of spring constant k and retract ve...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586549/ https://ncbi.nlm.nih.gov/pubmed/18757559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.137141 |
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