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Fibronectin III 13-14 Domains Induce Joint Damage via Toll-Like Receptor 4 Activation and Synergize with Interleukin-1 and Tumour Necrosis Factor

Cartilage loss is a feature of chronic arthritis. It results from degradation of the extracellular matrix which is composed predominantly of aggrecan and type II collagen. Extracellular matrix degradation is mediated by aggrecanases and matrix metalloproteinases (MMPs). Recently, a number of endogen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sofat, Nidhi, Robertson, Saralili Dipa, Wait, Robin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: S. Karger AG 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250657/
https://ncbi.nlm.nih.gov/pubmed/21997473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329632
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