Fibronectin III 13-14 Domains Induce Joint Damage via Toll-Like Receptor 4 Activation and Synergize with Interleukin-1 and Tumour Necrosis Factor

Cartilage loss is a feature of chronic arthritis. It results from degradation of the extracellular matrix which is composed predominantly of aggrecan and type II collagen. Extracellular matrix degradation is mediated by aggrecanases and matrix metalloproteinases (MMPs). Recently, a number of endogen...

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Hlavní autoři: Sofat, Nidhi, Robertson, Saralili Dipa, Wait, Robin
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250657/
https://ncbi.nlm.nih.gov/pubmed/21997473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329632
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