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CUGBP1 and MBNL1 preferentially bind to 3′ UTRs and facilitate mRNA decay
CUGBP1 and MBNL1 are developmentally regulated RNA-binding proteins that are causally associated with myotonic dystrophy type 1. We globally determined the in vivo RNA-binding sites of CUGBP1 and MBNL1. Interestingly, CUGBP1 and MBNL1 are both preferentially bound to 3′ UTRs. Analysis of CUGBP1- and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250574/ https://ncbi.nlm.nih.gov/pubmed/22355723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00209 |
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