Defining human ERAD networks through an integrative mapping strategy

Proteins that fail to correctly fold or assemble into oligomeric complexes in the endoplasmic reticulum (ER) are degraded by a ubiquitin and proteasome dependent process known as ER-associated degradation (ERAD). Although many individual components of the ERAD system have been identified, how these...

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Bibliografische gegevens
Hoofdauteurs: Christianson, John C., Olzmann, James A., Shaler, Thomas A., Sowa, Mathew E., Bennett, Eric J., Richter, Caleb M., Tyler, Ryan E., Greenblatt, Ethan J., Harper, J. Wade, Kopito, Ron R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250479/
https://ncbi.nlm.nih.gov/pubmed/22119785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2383
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