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Epitope-Tagged Pkhd1 Tracks the Processing, Secretion, and Localization of Fibrocystin

Mutations in the PKHD1 gene, which encodes fibrocystin, cause autosomal recessive polycystic kidney disease (ARPKD). Unfortunately, the lack of specific antibodies to the mouse protein impairs the study of splicing, post-translational processing, shedding, and temporal and spatial expression of endo...

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Bibliografiske detaljer
Main Authors: Bakeberg, Jason L., Tammachote, Rachaneekorn, Woollard, John R., Hogan, Marie C., Tuan, Han-Fang, Li, Ming, van Deursen, Jan M., Wu, Yanhong, Huang, Bing Q., Torres, Vicente E., Harris, Peter C., Ward, Christopher J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250208/
https://ncbi.nlm.nih.gov/pubmed/22021705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010111173
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