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An extracellular domain of the accessory β1 subunit is required for modulating BK channel voltage sensor and gate

A family of tissue-specific auxiliary β subunits modulates large conductance voltage- and calcium-activated potassium (BK) channel gating properties to suit their diverse functions. Paradoxically, β subunits both promote BK channel activation through a stabilization of voltage sensor activation and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gruslova, Aleksandra, Semenov, Iurii, Wang, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250105/
https://ncbi.nlm.nih.gov/pubmed/22155735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110698
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