Nalaganje...
Mechanism of inhibition of connexin channels by the quinine derivative N-benzylquininium
The anti-malarial drug quinine and its quaternary derivative N-benzylquininium (BQ(+)) have been shown to inhibit gap junction (GJ) channels with specificity for Cx50 over its closely related homologue Cx46. Here, we examined the mechanism of BQ(+) action using undocked Cx46 and Cx50 hemichannels, w...
Shranjeno v:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2012
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250100/ https://ncbi.nlm.nih.gov/pubmed/22200948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110678 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|