TRAIL Gene-Armed Oncolytic Poxvirus and Oxaliplatin Can Work Synergistically against Colorectal Cancer

We have explored a unique combination therapy for metastatic colorectal cancer. This strategy combines a potent and new oncolytic poxvirus expressing a membrane-bound tumor necrosis factor-related apoptosis-inducing ligand (TRAIL or TNFSF10) and oxaliplatin (Ox) chemotherapy. We hypothesized that TR...

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Detalhes bibliográficos
Main Authors: Ziauddin, Mohammed F, Guo, Z. Sheng, O'Malley, Mark E., Austin, Frances, Popovic, Petar J., Kavanagh, Maihgan A., Li, Jun, Sathaiah, Magesh, Thirunavukkarasu, Prag, Fang, Bingliang, Lee, Yong J., Bartlett, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250063/
https://ncbi.nlm.nih.gov/pubmed/20182517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.5
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