TRAIL Gene-Armed Oncolytic Poxvirus and Oxaliplatin Can Work Synergistically against Colorectal Cancer

We have explored a unique combination therapy for metastatic colorectal cancer. This strategy combines a potent and new oncolytic poxvirus expressing a membrane-bound tumor necrosis factor-related apoptosis-inducing ligand (TRAIL or TNFSF10) and oxaliplatin (Ox) chemotherapy. We hypothesized that TR...

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Bibliographic Details
Main Authors: Ziauddin, Mohammed F, Guo, Z. Sheng, O'Malley, Mark E., Austin, Frances, Popovic, Petar J., Kavanagh, Maihgan A., Li, Jun, Sathaiah, Magesh, Thirunavukkarasu, Prag, Fang, Bingliang, Lee, Yong J., Bartlett, David L.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250063/
https://ncbi.nlm.nih.gov/pubmed/20182517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.5
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