TSH Regulates Pendrin Membrane Abundance and Enhances Iodide Efflux in Thyroid Cells

Thyroid hormones are essential for normal development and metabolism. Their synthesis requires transport of iodide into thyroid follicles. The mechanisms involving the apical efflux of iodide into the follicular lumen are poorly elucidated. The discovery of mutations in the SLC26A4 gene in patients...

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Autores principales: Pesce, Liuska, Bizhanova, Aigerim, Caraballo, Juan Carlos, Westphal, Whitney, Butti, Maria L., Comellas, Alejandro, Kopp, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2012
Materias:
Thyroid-TRH-TSH
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249672/
https://ncbi.nlm.nih.gov/pubmed/22109890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1548
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