Induction of steroid sulfatase expression by tumor necrosis factor-α through phosphatidylinositol 3-kinase/Akt signaling pathway in PC-3 human prostate cancer cells

Steroid sulfatase (STS) is responsible for the hydrolysis of aryl and alkyl steroid sulfates and has a pivotal role in regulating the formation of biologically active estrogens. STS may be considered a new promising drug target for treating estrogen-mediated carcinogenesis. However, the molecular me...

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Main Authors: Suh, Bo-Young, Jung, Jin-Joo, Park, Nahee, Seong, Cheul-Hun, Im, Hee-Jung, Kwon, Yeojung, Kim, Donghak, Chun, Young-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249591/
https://ncbi.nlm.nih.gov/pubmed/21904110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2011.43.11.073
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