Acetylation of αA-crystallin in the human lens: Effects on structure and chaperone function

α-Crystallin is a major protein in the human lens that is perceived to help to maintain the transparency of the lens through its chaperone function. In this study, we demonstrate that many lens proteins including αA-crystallin are acetylated in vivo. We found that K70 and K99 in αA-crystallin and, K...

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Hauptverfasser: Nagaraj, Ram H., Nahomi, Rooban B., Shanthakumar, Shilpa, Linetsky, Mikhail, Padmanabha, Smitha, Pasupuleti, Nagarekha, Wang, Benlian, Santhoshkumar, Puttur, Panda, Alok Kumar, Biswas, Ashis
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249504/
https://ncbi.nlm.nih.gov/pubmed/22120592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.11.011
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