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Chaperone Peptides of α-Crystallin Inhibit Epithelial Cell Apoptosis, Protein Insolubilization, and Opacification in Experimental Cataracts

α-Crystallin is a member of the small heat-shock protein (sHSP) family and consists of two subunits, αA and αB. Both αA- and αB-crystallin act as chaperones and anti-apoptotic proteins. Previous studies have identified the peptide (70)KFVIFLDVKHFSPEDLTVK(88) in αA-crystallin and the peptide (73)DRFS...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Nahomi, Rooban B., Wang, Benlian, Raghavan, Cibin T., Voss, Oliver, Doseff, Andrea I., Santhoshkumar, Puttur, Nagaraj, Ram H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642345/
https://ncbi.nlm.nih.gov/pubmed/23508955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.440214
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