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Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle’s cycle

Right ventricular hypertrophy (RVH) and RV failure are major determinants of prognosis in pulmonary hypertension and congenital heart disease. In RVH, there is a metabolic shift from glucose oxidation (GO) to glycolysis. Directly increasing GO improves RV function, demonstrating the susceptibility o...

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Detaylı Bibliyografya
Asıl Yazarlar: Fang, Yong-Hu, Piao, Lin, Hong, Zhigang, Toth, Peter T., Marsboom, Glenn, Bache-Wiig, Peter, Rehman, Jalees, Archer, Stephen L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249482/
https://ncbi.nlm.nih.gov/pubmed/21874543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0804-9
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