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Characterizing complex structural variation in germline and somatic genomes

Genome structural variation (SV) is a major source of genetic diversity in mammals and a hallmark of cancer. While SV is typically defined by its canonical forms – duplication, deletion, insertion, inversion and translocation – recent breakpoint mapping studies have revealed a surprising number of “...

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Bibliografiske detaljer
Main Authors: Quinlan, Aaron R., Hall, Ira M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249479/
https://ncbi.nlm.nih.gov/pubmed/22094265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2011.10.002
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