Patterns of somatic structural variation in human cancer genomes

A key mutational process in cancer is structural variation, in which rearrangements delete, amplify or reorder genomic segments that range in size from kilobases to whole chromosomes(1–7). Here we develop methods to group, classify and describe somatic structural variants, using data from the Pan-Ca...

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Vydáno v:Nature
Hlavní autoři: Li, Yilong, Roberts, Nicola D., Wala, Jeremiah A., Shapira, Ofer, Schumacher, Steven E., Kumar, Kiran, Khurana, Ekta, Waszak, Sebastian, Korbel, Jan O., Haber, James E., Imielinski, Marcin, Weischenfeldt, Joachim, Beroukhim, Rameen, Campbell, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025897/
https://ncbi.nlm.nih.gov/pubmed/32025012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1913-9
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