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Mechanism of translocation of uracil-DNA glycosylase from Escherichia coli between distributed lesions
Uracil-DNA glycosylase (Ung) is a DNA repair enzyme that excises uracil bases from DNA, where they appear through deamination of cytosine or incorporation from a cellular dUTP pool. DNA repair enzymes often use one-dimensional diffusion along DNA to accelerate target search; however, this mechanism...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249333/ https://ncbi.nlm.nih.gov/pubmed/21971549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.09.106 |
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