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Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57Bl6 Mice

The taxane chemotherapeutic paclitaxel frequently produces peripheral neuropathy in humans. Rodent models to investigate mechanisms and treatments are largely restricted to male rats, whereas female mouse studies are lacking. We characterized a range of paclitaxel doses on cold and mechanical allody...

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Main Authors: Ward, Sara Jane, Ramirez, Michael David, Neelakantan, Harshini, Walker, Ellen Ann
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249239/
https://ncbi.nlm.nih.gov/pubmed/21737705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3182283486
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