Cold Exposure Exacerbates Cardiac Dysfunction in a Model of Heart Failure with Preserved Ejection Fraction in Male and Female C57Bl/6J Mice

<b>Background</b>: Standard room temperature housing (~22 °C) represents a stress for laboratory mice, resulting in an increased metabolic rate, calorie consumption, heart rate, and catecholamine levels compared to thermoneutral conditions (29–32 °C). Using a recently established two-hit model of he...

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Detalles Bibliográficos

Principais autores:	Sara-Ève Thibodeau, Marie-Lune Legros, Emylie-Ann Labbé, Élisabeth Walsh-Wilkinson, Audrey Morin-Grandmont, Sarra Beji, Marie Arsenault, Alexandre Caron, Jacques Couet
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2025-08-01
Series:	Biomedicines
Assuntos:	housing temperature cold stress heart failure brown fat cardiac hypertrophy HFpEF
Acceso en liña:	https://www.mdpi.com/2227-9059/13/8/1900
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