The Loss of Gonadal Hormones Has a Different Impact on Aging Female and Male Mice Submitted to Heart Failure-Inducing Metabolic Hypertensive Stress

Background: Aging and the female sex are considered risk factors for the development of heart failure with preserved ejection fraction (HFpEF). Unlike other risk factors, such as hypertension, obesity, or diabetes, they do not represent therapeutic targets. Methods: In a recently developed two-hit m...

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Hauptverfasser:	Diwaba Carmel Teou, Emylie-Ann Labbé, Sara-Ève Thibodeau, Élisabeth Walsh-Wilkinson, Audrey Morin-Grandmont, Ann-Sarah Trudeau, Marie Arsenault, Jacques Couet
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-06-01
Schriftenreihe:	Cells
Schlagworte:	mouse heart failure sex differences cardiac hypertrophy aging preclinical model
Online-Zugang:	https://www.mdpi.com/2073-4409/14/12/870
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