Yeast Sterol Regulatory Element-binding Protein (SREBP) Cleavage Requires Cdc48 and Dsc5, a Ubiquitin Regulatory X Domain-containing Subunit of the Golgi Dsc E3 Ligase

Schizosaccharomyces pombe Sre1 is a membrane-bound transcription factor that controls adaptation to hypoxia. Like its mammalian homolog, sterol regulatory element-binding protein (SREBP), Sre1 activation requires release from the membrane. However, in fission yeast, this release occurs through a str...

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Detalhes bibliográficos
Main Authors: Stewart, Emerson V., Lloyd, S. Julie-Ann, Burg, John S., Nwosu, Christine C., Lintner, Robert E., Daza, Riza, Russ, Carsten, Ponchner, Karen, Nusbaum, Chad, Espenshade, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249121/
https://ncbi.nlm.nih.gov/pubmed/22086920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.317370
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