Trigeminal ganglion neuron subtype-specific alterations of Ca(V)2.1 calcium current and excitability in a Cacna1a mouse model of migraine

ABSTRACT: Familial hemiplegic migraine type-1 (FHM1), a monogenic subtype of migraine with aura, is caused by gain-of-function mutations in Ca(V)2.1 (P/Q-type) calcium channels. The consequences of FHM1 mutations on the trigeminovascular pathway that generates migraine headache remain largely unexpl...

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Detaylı Bibliyografya
Asıl Yazarlar: Fioretti, B, Catacuzzeno, L, Sforna, L, Gerke-Duncan, M B, van den Maagdenberg, A M J M, Franciolini, F, Connor, M, Pietrobon, D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2011
Konular:
Neuroscience: Neurobiology of Disease
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249056/
https://ncbi.nlm.nih.gov/pubmed/22005682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.220533
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