The ΔfbpA attenuated candidate vaccine from Mycobacterium tuberculosis, H37Rv primes for a stronger T-bet dependent Th1 immunity in mice

The ΔfbpA candidate vaccine derived from Mycobacterium tuberculosis (H37Rv) protects mice better than BCG against tuberculosis, and we investigated the hypothesis that ΔfbpA may induce a stronger Th1 immunity. Since T-bet transcription factor regulates Th1 immunity, mice infected with ΔfbpA, BCG vac...

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Main Authors: Roche, Cherie M., Smith, Amanda, Lindsey, Devin R., Meher, Akshay, Schluns, Kimberly, Arora, Ashish, Armitige, Lisa Y., Jagannath, Chinnaswamy
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248993/
https://ncbi.nlm.nih.gov/pubmed/22082615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2011.10.018
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