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Partially dominant mutant channel defect corresponding with intermediate Long-QT2 phenotype

BACKGROUND: The hereditary Long QT Syndrome (LQTS) is a common cardiac disorder where ventricular repolarization is delayed, abnormally prolonging the QTc interval on ECG. LQTS is linked to various genetic loci including the KCNH2 (HERG) gene that encodes the α–subunit of the cardiac potassium chann...

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Detalhes bibliográficos
Main Authors: Krishnan, Yamini, Zheng, Renjian, Walsh, Christine, Tang, YingYing, McDonald, Thomas V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248989/
https://ncbi.nlm.nih.gov/pubmed/21951015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8159.2011.03222.x
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