Inhibition of Noroviruses by Piperazine Derivatives

There is currently an unmet need for the development of small-molecule therapeutics for norovirus infection. The piperazine scaffold, a privileged structure embodied in many pharmacological agents, was used to synthesize an array of structurally-diverse derivatives which were screened for anti-norov...

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Bibliografske podrobnosti
Main Authors: Dou, Dengfeng, He, Guijia, Mandadapu, Sivakoteswara Rao, Aravapalli, Sridhar, Kim, Yunjeong, Chang, Kyeong-Ok, Groutas, William C.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248970/
https://ncbi.nlm.nih.gov/pubmed/22119464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.10.122
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