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T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility
Tell mediated immunity requires T cell receptor (TCR) cross-reactivity, the mechanisms behind which remain incompletely elucidated. The αβ TCR A6 recognizes both the Tax (LLFGYPVYV) and Tel1p (MLWGYLQYV) peptides presented by the human class I MHC molecule HLA-A2. Here we found that although the two...
Tallennettuna:
| Päätekijät: | , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248800/ https://ncbi.nlm.nih.gov/pubmed/20064447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.11.003 |
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