Probing transcription-specific outputs of β-catenin in vivo

β-Catenin, apart from playing a cell-adhesive role, is a key nuclear effector of Wnt signaling. Based on activity assays in Drosophila, we generated mouse strains where the endogenous β-catenin protein is replaced by mutant forms, which retain the cell adhesion function but lack either or both of th...

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Detalhes bibliográficos
Main Authors: Valenta, Tomas, Gay, Max, Steiner, Sarah, Draganova, Kalina, Zemke, Martina, Hoffmans, Raymond, Cinelli, Paolo, Aguet, Michel, Sommer, Lukas, Basler, Konrad
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248684/
https://ncbi.nlm.nih.gov/pubmed/22190459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.181289.111
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