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Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development

Bcl9 and Bcl9l (Bcl9/9l) encode Wnt signaling components that mediate the interaction between β-catenin and Pygopus (Pygo) via two evolutionarily conserved domains, HD1 and HD2, respectively. We generated mouse strains lacking these domains to probe the β-catenin-dependent and β-catenin-independent...

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Bibliografiske detaljer
Main Authors: Cantù, Claudio, Zimmerli, Dario, Hausmann, George, Valenta, Tomas, Moor, Andreas, Aguet, Michel, Basler, Konrad
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197948/
https://ncbi.nlm.nih.gov/pubmed/25184676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.246140.114
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