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Synthesis and evaluation of (18)F-labeled PPARγ antagonists

INTRODUCTION: Peroxisome proliferator activated-receptor gamma (PPARγ) transcriptionally modulates fat metabolism and also plays a role in pathological conditions such as cancer, neurodegenerative disease, and inflammation. PPARγ imaging agents are potential tools for investigating these diseases. M...

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Autori principali: Lee, Hsiaoju, Chen, Delphine L., Rothfuss, Justin M., Welch, Michael J., Gropler, Robert J., Mach, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248633/
https://ncbi.nlm.nih.gov/pubmed/21907585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2011.07.002
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