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Highly efficient click labeling using 2-[(18)F]fluoroethyl azide and synthesis of an (18)F N-hydroxysuccinimide ester as conjugation agent

INTRODUCTION: Click labeling using 2-[(18)F]fluoroethyl azide has been proven to be promising methods of radiolabeling small molecules and peptides, some of which are undergoing clinical evaluations. However, the previously reported method afforded low yield, poor purities and under desirable reprod...

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Bibliographic Details
Main Authors: Zhou, Dong, Chu, Wenhua, Dence, Carmen S., Mach, Robert H., Welch, Michael J.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468714/
https://ncbi.nlm.nih.gov/pubmed/22770647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.06.002
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