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Highly efficient click labeling using 2-[(18)F]fluoroethyl azide and synthesis of an (18)F N-hydroxysuccinimide ester as conjugation agent

INTRODUCTION: Click labeling using 2-[(18)F]fluoroethyl azide has been proven to be promising methods of radiolabeling small molecules and peptides, some of which are undergoing clinical evaluations. However, the previously reported method afforded low yield, poor purities and under desirable reprod...

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Detalhes bibliográficos
Principais autores: Zhou, Dong, Chu, Wenhua, Dence, Carmen S., Mach, Robert H., Welch, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468714/
https://ncbi.nlm.nih.gov/pubmed/22770647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.06.002
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