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Roles of Serotonergic and Adrenergic Receptors in the Antinociception of Selective Cyclooxygenase-2 Inhibitor in the Rat Spinal Cord

BACKGROUND: The analgesic mechanisms of cyclooxygenase (COX)-2 inhibitors have been explained mainly on the basis of the inhibition of prostaglandin biosynthesis. However, several lines of evidence suggest that their analgesic effects are mediated through serotonergic or adrenergic transmissions. We...

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Detalhes bibliográficos
Main Authors: Jeong, Hye Jin, Lee, Seong Heon, Cho, Soo Young, Lee, Cha Sup, Jeong, Cheol Won, Yoon, Myung Ha, Kim, Woong Mo
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Pain Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248580/
https://ncbi.nlm.nih.gov/pubmed/22220238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3344/kjp.2011.24.4.179
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