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Roles of Adenosine and Serotonin Receptors on the Antinociception of Sildenafil in the Spinal Cord of Rats

PURPOSE: The phosphodiesterase 5 inhibitor sildenafil has antinociceptive effects, mediated by an increase in cGMP. This study examined the role of spinal adenosine and serotonin receptors played in the antinociceptive effects of intrathecal sildenafil. MATERIALS AND METHODS: Intrathecal catheters w...

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Autori principali: Lee, Hyung Gon, Kim, Woong Mo, Park, Cheon Hee, Yoon, Myung Ha
Natura: Artigo
Lingua:Inglês
Pubblicazione: Yonsei University College of Medicine 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995964/
https://ncbi.nlm.nih.gov/pubmed/20879067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2010.51.6.960
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