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Additive Antinociception between Intrathecal Sildenafil and Morphine in the Rat Formalin Test

The possible characteristics of spinal interaction between sildenafil (phosphodiesterase 5 inhibitor) and morphine on formalin-induced nociception in rats was examined. Then the role of the opioid receptor in the effect of sildenafil was further investigated. Catheters were inserted into the intrath...

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Main Authors: Yoon, Myung Ha, Park, Kyung Deok, Lee, Hyung Gon, Kim, Woong Mo, An, Tae Hoon, Kim, Yeo Ok, Huang, Lan Ji, Hua, Cui Jin
Formato: Artigo
Idioma:Inglês
Publicado: The Korean Academy of Medical Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610640/
https://ncbi.nlm.nih.gov/pubmed/19119449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2008.23.6.1033
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