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Roles of Serotonergic and Adrenergic Receptors in the Antinociception of Selective Cyclooxygenase-2 Inhibitor in the Rat Spinal Cord

BACKGROUND: The analgesic mechanisms of cyclooxygenase (COX)-2 inhibitors have been explained mainly on the basis of the inhibition of prostaglandin biosynthesis. However, several lines of evidence suggest that their analgesic effects are mediated through serotonergic or adrenergic transmissions. We...

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Библиографические подробности
Главные авторы: Jeong, Hye Jin, Lee, Seong Heon, Cho, Soo Young, Lee, Cha Sup, Jeong, Cheol Won, Yoon, Myung Ha, Kim, Woong Mo
Формат: Artigo
Язык:Inglês
Опубликовано: The Korean Pain Society 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248580/
https://ncbi.nlm.nih.gov/pubmed/22220238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3344/kjp.2011.24.4.179
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