Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

More than 2% of adults harbor a pancreatic cyst, a subset of which progresses to invasive lesions with lethal consequences. To assess the genomic landscapes of neoplastic cysts of the pancreas, we determined the exomic sequences of DNA from the neoplastic epithelium of eight surgically resected cyst...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wu, Jian, Jiao, Yuchen, Dal Molin, Marco, Maitra, Anirban, de Wilde, Roeland F., Wood, Laura D., Eshleman, James R., Goggins, Michael G., Wolfgang, Christopher L., Canto, Marcia I., Schulick, Richard D., Edil, Barish H., Choti, Michael A., Adsay, Volkan, Klimstra, David S., Offerhaus, G. Johan A., Klein, Alison P., Kopelovich, Levy, Carter, Hannah, Karchin, Rachel, Allen, Peter J., Schmidt, C. Max, Naito, Yoshiki, Diaz, Luis A., Kinzler, Kenneth W., Papadopoulos, Nickolas, Hruban, Ralph H., Vogelstein, Bert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248495/
https://ncbi.nlm.nih.gov/pubmed/22158988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118046108
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