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Efficient Maximum Likelihood Estimation of Kinetic Rate Constants from Macroscopic Currents
A new method is described that accurately estimates kinetic constants, conductance and number of ion channels from macroscopic currents. The method uses both the time course and the strength of correlations between different time points of macroscopic currents and utilizes the property of semisepara...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248447/ https://ncbi.nlm.nih.gov/pubmed/22242142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029731 |
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