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The quality of maximum likelihood estimates of ion channel rate constants

Properties of maximum likelihood estimators of rate constants for channel mechanisms are investigated, to see what can and cannot be inferred from experimental results. The implementation of the HJCFIT method is described; it maximises the likelihood of an entire sequence of apparent open and shut t...

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Detaylı Bibliyografya
Asıl Yazarlar: Colquhoun, D, Hatton, C J, Hawkes, A G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342730/
https://ncbi.nlm.nih.gov/pubmed/12562901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.034165
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