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Efficient Maximum Likelihood Estimation of Kinetic Rate Constants from Macroscopic Currents

A new method is described that accurately estimates kinetic constants, conductance and number of ion channels from macroscopic currents. The method uses both the time course and the strength of correlations between different time points of macroscopic currents and utilizes the property of semisepara...

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Bibliografiska uppgifter
Huvudupphovsmän: Stepanyuk, Andrey R., Borisyuk, Anya L., Belan, Pavel V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248447/
https://ncbi.nlm.nih.gov/pubmed/22242142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029731
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