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Probing the SELEX Process with Next-Generation Sequencing
BACKGROUND: SELEX is an iterative process in which highly diverse synthetic nucleic acid libraries are selected over many rounds to finally identify aptamers with desired properties. However, little is understood as how binders are enriched during the selection course. Next-generation sequencing off...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248438/ https://ncbi.nlm.nih.gov/pubmed/22242135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029604 |
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