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Knockout of 5-Lipoxygenase Results in Age-Dependent Anxiety-Like Behavior in Female Mice

BACKGROUND: The enzyme 5-lipoxygenase (5LO) has been implicated in a variety of neurological and psychiatric disorders including anxiety. Knockout of 5LO has previously been shown to alter anxiety-like behavior in mice at a young age but the effect of 5LO knockout on older animals has not been chara...

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Autors principals: Joshi, Yash B., Praticò, Domenico
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248425/
https://ncbi.nlm.nih.gov/pubmed/22220211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029448
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