Age-Dependent Relevance of Endogenous 5-Lipoxygenase Derivatives in Anxiety-Like Behavior in Mice

When 5-lipoxygenase (5-LO) is inhibited, roughly half of the CNS effect of the prototypic endocannabinoid anandamide (AEA) is lost. Therefore, we decided to investigate whether inhibiting this enzyme would influence physiological functions classically described as being under control of the endocann...

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Detalhes bibliográficos
Main Authors: Leo, Luciana M., Almeida-Corrêa, Suellen, Canetti, Claudio A., Amaral, Olavo B., Bozza, Fernando A., Pamplona, Fabricio A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885659/
https://ncbi.nlm.nih.gov/pubmed/24416334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085009
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