Age-Dependent Relevance of Endogenous 5-Lipoxygenase Derivatives in Anxiety-Like Behavior in Mice

When 5-lipoxygenase (5-LO) is inhibited, roughly half of the CNS effect of the prototypic endocannabinoid anandamide (AEA) is lost. Therefore, we decided to investigate whether inhibiting this enzyme would influence physiological functions classically described as being under control of the endocann...

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Main Authors: Leo, Luciana M., Almeida-Corrêa, Suellen, Canetti, Claudio A., Amaral, Olavo B., Bozza, Fernando A., Pamplona, Fabricio A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885659/
https://ncbi.nlm.nih.gov/pubmed/24416334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085009
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