Загрузка...
c-JUN prevents methylation of p16INK4a (and Cdk6): the villain turned bodyguard
A novel way by which the AP-1 factor c-JUN interferes with tumorigenesis has recently been elucidated [1]. In a model of murine leukemia, c-JUN prevents the epigenetic silencing of the cell cycle kinase CDK6. In the absence of c-JUN, CDK6 is down-regulated and the 5'region of the gene is methyl...
Сохранить в:
| Главные авторы: | , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2011
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248190/ https://ncbi.nlm.nih.gov/pubmed/21789792 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|