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Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link

The proteasome inhibitor Bortezomib has been identified as a potent enhancer of TRAIL-induced apoptosis in several human cancers. However, the identification of the underlying molecular mechanisms of this synergistic cell death induction has been ongoing over the last years. A recent study identifie...

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Autor principal: Fulda, Simone
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248183/
https://ncbi.nlm.nih.gov/pubmed/21789791
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