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Improved HILIC LC/MS of Heparinoids using a Chip with Post-column Make-up Flow

Heparan Sulfate (HS) and heparin are linear, heterogeneous carbohydrates of the glycosaminoglycan (GAG) family that are modified by N-acetylation, N-sulfation, O-sulfation, and uronic acid epimerization. HS interacts with growth factors in the extracellular matrix, thereby modulating signaling pathw...

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Detalhes bibliográficos
Main Authors: Staples, Gregory O., Naimy, Hicham, Yin, Hongfeng, Kileen, Kevin, Kraiczek, Karsten, Costello, Catherine E., Zaia, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247906/
https://ncbi.nlm.nih.gov/pubmed/20000724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac901706f
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