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A Chip-based Amide-HILIC LC/MS Platform for Glycosaminoglycan Glycomics Profiling

A key challenge to investigations into the functional roles of glycosaminoglycans (GAGs) in biological systems is the difficulty in achieving sensitive, stable and reproducible mass spectrometric analysis. GAGs are linear carbohydrates with domains that vary in the extent of sulfation, acetylation a...

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Detalhes bibliográficos
Main Authors: Staples, Gregory O., Bowman, Michael J., Costello, Catherine E., Hitchcock, Alicia M., Lau, James M., Leymarie, Nancy, Miller, Christine, Naimy, Hicham, Shi, Xiaofeng, Zaia, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771417/
https://ncbi.nlm.nih.gov/pubmed/19137549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200701008
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