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Improved LC-MS/MS of Heparan Sulfate Oligosaccharides via Chip-based Pulsed Make-up Flow

Microfluidic chip-based hydrophilic interaction chromatography (HILIC) is a useful separation system for liquid chromatography-mass spectrometry (LC-MS) in compositional profiling of heparan sulfate (HS) oligosaccharides; however, ions observed using HILIC LC-MS are low in charge. Tandem MS of HS ol...

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Bibliographic Details
Main Authors: Huang, Yu, Shi, Xiaofeng, Yu, Xiang, Leymarie, Nancy, Staples, Gregory O., Yin, Hongfeng, Killeen, Kevin, Zaia, Joseph
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205275/
https://ncbi.nlm.nih.gov/pubmed/21923145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201964n
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