A Viral Vectored Prime-Boost Immunization Regime Targeting the Malaria Pfs25 Antigen Induces Transmission-Blocking Activity

The ookinete surface protein Pfs25 is a macrogamete-to-ookinete/ookinete stage antigen of Plasmodium falciparum, capable of exerting high-level anti-malarial transmission-blocking activity following immunization with recombinant protein-in-adjuvant formulations. Here, this antigen was expressed in r...

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Main Authors: Goodman, Anna L., Blagborough, Andrew M., Biswas, Sumi, Wu, Yimin, Hill, Adrian V., Sinden, Robert E., Draper, Simon J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247263/
https://ncbi.nlm.nih.gov/pubmed/22216279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029428
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